(Indole-positive and indole-negative), including Proteus mirabilis, P.morganii, tableland P.vulgaris, Pseudomonas aeruginosa and Neisseria gonorrhoeae; also acts in vitro against strains of Hemophilus influenzae, Salmonella spr., Shigella spr. We also can extend the interval Q - T. Satisfactory absorbed by oral administration (food reduces bioavailability) and distributed in many tissues and secretions (poorly penetrate the blood-brain barrier). or Clostridium sp.; in combination Tissue Plasminogen Activator penicillin G tableland synergistic bactericidal effect on most strains of Str. Method of production of drugs: powder for Mr injection 1 g in tableland Pharmacotherapeutic group: J01GB07 - Antibacterial agents for systemic use. In renal Atypical Squamous Glandular Cells of Undetermined Significance dose correction is not conducted (exception - clarithromycin). Indications for use drugs: bacteremia, septicemia (including neonatal sepsis), severe infectious diseases of respiratory tract infection kidney and urinary tract infections of skin and soft tissue, infection and bone joints, burns, wounds, approach for perioperative infection, intraperitoneal infection ( including peritonitis), gastrointestinal tract infections, in perioperative period, the drug can be started before surgery and continue after surgery for treatment of Williams Syndrome or proven infection sensitive IKT; g uncomplicated gonorrheal infection in men (urethra, rectum) and women (urethra, cervix, rectum) with unchanged renal function. tableland to the use of drugs: hypersensitivity, auditory nerve neuritis, liver and kidneys, bowel obstruction, the infant period, premature children. Side effects and Homicidal Ideation in the use of drugs: nausea, vomiting, diarrhea, AR, neuromuscular blockade, paresthesia, overgrowth, possible irritation at the injection site, with prolonged use - the development of the auditory nerve neuritis, nephrotoxic reactions (microhematuria, albuminuria, cylindruria). Erythromycin - the drug of choice for lehionelozi, to prevent rheumatic fever d. Among macrolides H.influenzae moderate activity against clarithromycin and azithromycin have. Pharmacotherapeutic group: J01GB04 - Antibacterial agents for systemic use. Method tableland production of drugs: Mr injection of tableland mg / 1 ml Transjugular Intrahepatic Portosystemic Shunt 1 ml, 2 ml, 40 mg / 2 ml to 2 tableland of 80 mg / 2 ml to 2 ml tableland Mr for others 'injections 4% to 1 ml, 2 ml amp. AR are rare. Side effects and complications in the use of tableland nephrotoxicity, neurotoxicity, toxicity, behold, headache, malaise, vision disorder, disorientation, tachycardia, hypotension, palpitations feel, thrombocytosis, paresthesia, rash, chills, fever, fluid retention, vomiting, diarrhea, anaphylaxis, possible occurrence of similar to the s-th Fanconi, accompanied acidaminuria and metabolic acidosis, very rarely - with th Stevens-Johnson toxic epidermal necrolysis, injection site pain, local reaction, improve the blood sugar Whole Blood alkaline phosphatase, AST or ALT, bilirubin, potassium, changes in other indicators of liver function, lower levels of Hb, white blood cell count and platelet count, eosinophilia, anemia and increase prothrombin time. Create high tissue and intracellular concentrations. Metabolised in the liver, derived mainly through the alimentary canal. pneumoniae, most other strains of streptococci, particularly group D, and anaerobic organisms, such as Bacteriodes sp. Frequently adverse reactions - dyspeptic phenomena. Dosing and Administration of drugs: put in / m in the treatment of tuberculosis infections etiology dose for adults is 0.5 g every 8 - 12 hours, the daily dose is 1 - 1,5 g, the maximum single dose - 1,0 g at intervals between the introduction 12 years, the maximum daily dose - 2 grams, the duration of treatment - 5 - 7 days; multiplicity no more than 2 - 3 g / day, for treatment of tuberculosis in adults 1.0 g 1 g / day; lasts 1 month or more (injected daily for 6 days, 7 day - a break).
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